Our vision is to make genomic information ubiquitous through an innovative, software-first approach

1
Library preparation
The first step is to prepare your population’s DNA samples. For the library preparation, we provide the necessary protocols and consultative services depending on your sequencing hardware.
2
Low-pass whole genome sequencing
Next, the genome is randomly sequenced but at shallower depths hence the name low-coverage or low-pass sequencing. We have three options for sequencing your samples: in our lab, our preferred network of service providers, or you may directly upload a FastQ file to the Gencove platform. Our lightning-fast speeds and multiple upload paths ensure this step is simple.
3
Imputation and analysis
Once the low-pass data is uploaded to the Gencove platform, it is compared to a fully sequenced and assembled standard haplotype genome of that particular organism. This step, called imputation, results in millions of over 99% accurate variant calls for every sample. Gencove builds comprehensive reference panels and continually enhances our data sets and algorithms to ensure the highest performing imputation. To further extend the value of your investment, we offer additional analysis, without the hassle of designing and developing another array. Now, your team can focus on innovation instead of struggling with the mechanics of large-scale genomic data analysis.
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Professional
Species-specific* packagesEach species package evolves over time as we process more samples, please refer to our Technical Documentation for the latest information.
- Human sequencing projects includes copy number variation (CNV) analysis, ancestry analysis, and computation of select polygenic risk scores.
- Cattle genomics covers breed analysis and additional polymorphisms.
- Canine package includes breed analysis.
- Maize sequencing package has strain analysis and multi-allelic SNPs.
- Rat sequencing includes strain analysis.
- Gencove platform access
- FastQ file uploads
- Multiple quality checks
Single user
Data access and management
- API or CLI
Low-pass sequencing
- Aligned BAM
- Imputed VCF to reference genomes
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Business
Species-specific* packagesEach species package evolves over time as we process more samples, please refer to our Technical Documentation for the latest information.
- Human sequencing projects includes copy number variation (CNV) analysis, ancestry analysis, and computation of select polygenic risk scores.
- Cattle genomics covers breed analysis and additional polymorphisms.
- Canine package includes breed analysis.
- Maize sequencing package has strain analysis and multi-allelic SNPs.
- Rat sequencing includes strain analysis.
- Gencove platform access
- FastQ file uploads
- Multiple quality checks
Unlimited users
Data access and management
- API or CLI
- Special sharing and permissions
- Webhooks and custom notifications
- Merged VCF
Low-pass sequencing
- Aligned BAM
- Imputed VCF to reference genomes
Advanced analytics
- Custom developed haplotype reference panel for your sole use
Client support and services
- Library prep: training manuals and onboarding resources
- Dedicated success manager
Get a quote >
Enterprise
Species-specific* packagesEach species package evolves over time as we process more samples, please refer to our Technical Documentation for the latest information.
- Human sequencing projects includes copy number variation (CNV) analysis, ancestry analysis, and computation of select polygenic risk scores.
- Cattle genomics covers breed analysis and additional polymorphisms.
- Canine package includes breed analysis.
- Maize sequencing package has strain analysis and multi-allelic SNPs.
- Rat sequencing includes strain analysis.
- Gencove platform access
- FastQ file uploads
- Multiple quality checks
Unlimited users
Data access and management
- API or CLI
- Special sharing and permissions
- Webhooks and custom notifications
- Merged VCF
- HIPAA/Audit trails
- Single tenant infrastructure
- Extended data lifecycle management
- Compliance agreements
Low-pass sequencing
- Aligned BAM
- Imputed VCF to reference genomes
- Targeted capture or Exome upgrade
Advanced analytics
- Custom developed haplotype reference panel for your sole use
- Proprietary Polygenic Risk Scoring
- Associate genetic variation with phenotypes for Genome-Wide Association Studies (GWAS)
- Novel Variant Detection**Low-coverage comparisons within a population to detect novel variants.
- Germline variant calling (WGS, WES)***Low-coverage comparisons within a population to detect novel variants.
- Somatic variant calling (Tumor/Normal)****Contact us
- Microbiome profiling****Contact us
Client support and services
- Library prep: training manuals and onboarding resources
- Dedicated success manager
- Custom sequencing protocol development
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Start with ready-to-run or custom pipelines
Choose an existing pipeline or work with Gencove’s scientists to optimize the platform for your application
Select the appropriate deployment model that fits your needs
End-to-end
From biological sample to data through our sequencing partners that have already integrated with Gencove
In-house
Set up the low-pass lab workflow in your lab and seamlessly use the Gencove imputation and analysis SaaS
SaaS-only
Integrate Gencove directly with your existing systems or greenfield deployments
Cloud-scale
Gencove is cloud-native, meaning end-to-end analysis is done in the cloud
Security
Rest assured Gencove is using industry-accepted best practices and frameworks
Compliance
Gencove is HIPAA compliant and aligns itself with ISO27001 and SOC2
Speed
Fast analytics together with lightning-fast uploads and downloads through CLI tools
Collaboration
Share projects with colleagues across your organization
Integration
Integrate directly with our API for production-ready workloads
Customization
Private configurations and reference panels for custom populations can be made available
Support
If you run into a snag, our team is there to help quickly and efficiently