We recently reported on the release of the novel gnomAD_v3.1.2 HGDP1KG human reference panel for build GRCh38. This new panel consists of a total of 4091 individuals, and we have previously discussed its considerable gains in imputation power when compared to other publicly available human reference panels.
We have now made the HGDP1KG panel available for build GRCh37. The GRCh37 version consists of a total of 78,752,417 variants lifted over from GRCh38. In a similar set of analyses to that used to evaluate the GRCh38 version, we demonstrate that the new dataset achieves superior performance to that of the prior instantiation of our human GRCh37 panel (consisting of the 1000 Genomes Project Phase III (1KG) samples only).