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Genomics Unmuted: The impact on clinical success from the 23andMe cohort
90% of therapeutic programs in clinical trials fail. Human genetic variation offers "natural experiments" that can inform successful therapeutic strategies with drug targets backed by human genetics 2-3 times more likely to succeed in the clinic. 23andMe has a dataset about ten times larger than current public cohorts, with approximately 15 million genotyped individuals, 80% of whom consent to research. In this session, you'll hear from Xin Wang, Ph.D., senior research scientist in statistical genetics at 23andMe as she explores how the scale of genetic data and improved methods to link genetic associations to causal genes impact clinical success predictions.
Plant and animal genomics
Genomics Unmuted: Low-pass whole genome sequencing plus capture as the next great tool for canine genomics
Dog research is at a crossroads. Like in humans, genetic tools could revolutionize veterinary care and improve the health and welfare of all dogs. However, widely used genetic testing services don’t provide researchers with the necessary information to achieve this vision. In this webinar, hear from Dr. Elinor Karlsson, who discusses a collaboration between Gencove, genomic scientists, and dog breeders. They have developed a new solution that combines high-accuracy genetic testing with comprehensive whole genome genotyping. This dual-purpose product supports breed ancestry analysis, Mendelian disease testing, and large-scale genomics.
Human genomics
Genomics Unmuted: Genetic profiling and polygenic risk score performance evaluation in the multi-ethnic population of the Kahn Sagol Maccabi Biobank
Coupling rich electronic health record data with the ability to sequence patients of interest is key to the identification of molecular signatures of specific populations and their application to drug discovery. In our latest webinar, Olivia Sabik from Valo Health shares how their collaboration with Kahn-Sagol-Maccabi (KSM), Maccabi Healthcare Services' Research and Innovation Center, offers an unparalleled opportunity to identify patient cohorts using deep longitudinal data. She discusses how the unique population history of these cohorts provides an opportunity for groundbreaking discoveries and how Valo Health is leveraging the Gencove platform to accelerate this discovery.
Human genomics
Genomics Unmuted: A Harmonized Public Resource of Deeply Sequenced Diverse Human Genomes
In this session, Mary T. Yohannes and Zan Koenig from the Broad Institute discuss their recent work on the harmonization of the Human Genome Diversity Project (HGDP) and the 1000 Genomes Project (1kGP) datasets. They highlight how this combination has led to significant advancements in understanding global genetic diversity, how it can benefit the study of underrepresented populations, and the cataloging of millions of new genetic variants. Additionally, Jeremy Li, Director of Data Science at Gencove, presents an analysis of the combined HGDP and 1kGP reference panel and how it can enhance the accuracy and efficiency of low-pass whole genome imputation.
Genomics Unmuted: Transforming Genetic Data Management and Utilization with Explorer Analysis Cloud
In this webinar Gencove's Head of Product, Geoff Benton dives into how Explorer empowering data science teams and reshaping the landscape of genetic data analytics and management.
At Gencove, we have repeatedly seen the complexity and insufficiency of existing tools limit research teams from fully unlocking the value of their genetic data. Gencove Explorer analysis cloud represents a full-stack solution that addresses the challenges that exist with currently data solutions, in a single integrated platform and with a minimal learning curve. In doing so, Explorer accelerates the rate at which scientists can answer critical biological questions, and furthers our goal of delivering insights that advance global health and sustainability.
Human genomics
Genomics Unmuted: Providing Newfound Resolution into Complex Human Phenotypes with GWAS and PRS-PheWAS
Genome-Wide-Association Studies (GWAS) require large-scale cohorts with both phenotype and genetic sequencing data, which has limited studied phenotypes. In this session, Zachary Levine from the Weizmann Institute of Science will delve into the outcomes of their GWAS and PRS-PheWAS involving 727 clinical phenotypes and 4,045 molecular features from the Human Phenotype Project. Join us to learn more about previously unlinked clinical traits and the study's utilization of low-pass whole genome sequencing, which has brought forth fresh insights into the intricate genetic architecture governing complex human phenotypes
Plant and animal genomics
Genomics Unmuted: Unlocking the Future of Sequencing in Agriculture
The Element AVITI System and Gencove's analytics platform are the perfect pair for cost-effective and comprehensive genotyping of crops and livestock. Watch this on-demand webinar to hear from Meredith Ashby PhD, Element Biosciences and Jesse Hoff, Gencove as they explore solutions that bring affordable sequencing to benefit agriculture.
Plant and animal genomics
Genomics Unmuted: How TMG identified resistance to soybean cyst nematode
How Dr. João Vitor Maldonado dos Santos and his team at TMG used Gencove’s low-pass sequencing platform to map resistance to soybean cyst nematode, one of the most economically damaging pests in soybean.
Human genomics
Genomics Unmuted: The science behind the identification of the Golden State Killer
Learn how Barbara Rae-Venter uses a suite of genetic genealogy tools in her pioneering work reviving cold cases showcased in her new book, I Know Who You Are.
Human genomics
Genomics Unmuted: Psomagen and Gencove show how to get cost-effective WGS
Many in the genomics industry are developing technologies to drive down the cost of whole genome sequencing. Gencove has developed a software solution that delivers high-throughput, cost-effective whole genome sequencing data and analysis. Learn how.
Human genomics
Genomics Unmuted: Dr. Joe Pickrell and Dr. Tomaz Berisa introduce Gencove
Gencove's low-pass whole genome sequencing and proprietary software-as-a-service computation layer delivers high-quality variant calls to help develop life-saving therapeutics or accelerate breeding programs to improve our global food supply.
Plant and animal genomics
Genomics Unmuted: Dr. Ellie Armstrong discusses the genomics of captive tigers
Dr. Ellie Armstrong, a Postdoctoral Fellow at Washington State University, discusses her range-wide assessments for both tigers and lions, in addition to profiles of individuals in captivity for tigers, most recently popularized by the Netflix drama ‘Tiger King’.
Human genomics
Genomics Unmuted: Element Biosciences and Gencove talk lpWGS applications
Dr. Shawn Levy, SVP of Applications & Scientific Affairs at Element Biosciences, and Dr. Joe Pickrell, Co-founder, and CEO of Gencove discuss how new and disruptive DNA sequencing platforms have the potential to revolutionize access to genomic information globally.
Human genomics
Genomics Unmuted: BGI and Gencove discuss data published in Genome Research
See the published data comparing the BGI DNBSEQ and Gencove’s low-pass whole genome sequencing and imputation platform to other ways to obtain genomic information
Plant and animal genomics
Genomics Unmuted: Dr. Brock Harpur and bee genomics
Learn how low-pass whole genome sequencing is helping to understand the genes and gene networks that regulate reproductive variation in honey bees, an important first step to incorporating genomic selection into bee breeding. See low-pass sequencing data on bee ancestry and bee genomics.
Human genomics
Utilizing a multiomics approach for new insight into ancestry effects on genetic immune responses
How the powerful combination of low pass whole genome sequencing (LPWGS) and single-cell sequencing can power new insights in evolutionary immunogenomics.