At WCGALP in Rotterdam? Meet us in booth 4

The sequencing read

Jesse Hoff, Agrigenomics Product Manager - Jun 15, 2022

A Modern Approach to Genotyping for Plant and Animal Breeding

There’s no question that sequencing is a powerhouse of utility for genetics in breeding. However, does it meet the requirements to become a routine tool for genomic selection in breeding programs?

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Josh Setton, Head of Sales - Jun 09, 2022

Three Ways Gencove’s Low-Pass Whole Genome Sequencing is Modernizing the Drug Discovery Process

Pharmaceutical companies use Whole Exome Sequencing (WES) in their drug discovery and development process. However, R&D teams still need a comprehensive view of genomic variation outside the exome. Historically, the only way to augment WES was with arrays, but now pharma companies have an alternative - low-pass whole genome sequencing.

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Jesse Hoff, Agrigenomics Product Manager - Jun 02, 2022

The First EPD for Bovine Congestive Heart Failure from Simplot and Gencove

The Simplot and Gencove genomic EPD provides a benchmark from which bulls can be evaluated for cardiac morphology significantly reducing their calves’ morbidity and mortality and increasing their overall economic performance.

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Kristi Ashton, Head of Marketing - Jun 01, 2022

Gencove and Element Biosciences, Inc., Reduce the Cost and Complexity of Obtaining Genomic Information

To offer another option for scientists and companies seeking whole genome sequencing and analysis, Gencove evaluated the ability to process low-pass sequencing data derived from the AVITI™ System in two studies.


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Jesse Hoff, Agrigenomics Product Manager - May 12, 2022

Introducing InfiniSEEK - Low-pass Genotyping Plus Target Capture in One Assay

Whether it is genotyping a whole herd or building support for new species and breeds, at Gencove, we’re continually looking for ways to empower companies and scientists to discover more using sequencing. That’s why we’re excited to share the latest milestone in this pursuit with the launch of InfiniSEEK™– available now through NEOGEN.

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Jesse Hoff, Agrigenomics Product Manager - Apr 28, 2022

Using a Modern Approach to Genotyping to Challenge Breed Stereotypes in Dogs

Do you rate your golden retrievers high on the scale for friendliness to strangers because they’ve been bred to demonstrate that trait or because you house an internal bias that tells you golden retrievers are friendly? These are precisely the types of questions that researchers are answering by utilizing modern, genome-wide sequencing information to better understand the association between genes and traits in dogs.

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Miguel Liezun, Software Engineer - Apr 12, 2022

Fetching subsets of VCF files, a DIY approach

The vision of Gencove is that the universal application of genomics will result in a healthier and more sustainable civilization.

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Miguel Liezun, Software Engineer - Oct 27, 2021

Importing samples from Amazon S3

At Gencove, we are committed to making genome sequencing more accessible. To that end, we are pleased to announce the ability to use Amazon S3 directly as an import origin in addition to supporting uploads through our CLI, our API, or from BaseSpace. The new feature saves time because samples can now be imported directly from an S3 bucket without the need to download and then upload again. In this post, we show how to import samples from a S3 URI to a project.

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Tomaz Berisa, CTO - Jul 04, 2021

Project-level permissions

tl;dr: users’ permissions can now be escalated on a per-project basis and auditing user access has become easier.

We’ve recently released an upgrade to Gencove’s permission system, which enables escalating permissions on a per-project basis. This is done by specifying a project-specific role in addition to the user’s organization role and can be done separately for each project in the organization.

For example, in a situation where the organization would like users to have view access to only a subset of projects, users with the Owner role in the organization would invite others to join the organization with the Member or Uploader role and assign project-specific Viewer roles as needed.

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Joe Pickrell, CEO - May 20, 2021

The coming commoditization of genome sequencing

tl;dr: new competition in genome sequencing hardware will drive expanded use cases for sequencing analytics across industries

In Nature’s Metropolis, the brilliant economic history of Chicago, William Cronon describes the shifts in power between agricultural producers and different industrial groups as technologies like the grain elevator upended traditional market relationships.

In this telling, a set of small steps gradually severed the connection between the buyer of a grain like corn and its original source — while in 1850 someone might buy a bag of corn from an individual producer and know that each individual kernel came from a specific plot of land, by 1880 that same buyer would likely be buying a quantity of "Number 2", pooled from corn produced in any number of anonymous locations.

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Jeremy Li, Head of Data Science - Mar 16, 2021

New imputation pipeline using newly resequenced data from 3202 individuals

The 1000 Genomes Project was completed in 2015 and culminated in its "phase 3 release" of phased genotypes from 2504 individuals at over 80 million variants, and remains the largest fully open-sourced genomic dataset [0]. The final variant callset was based on a combination low-coverage whole-genome sequencing (at an average of around 7x) along with whole exome sequencing and results from genotyping array assays of these individuals.

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Jeremy Li, Head of Data Science - Mar 11, 2021

New publication in collaboration with the USDA: "Assessment of Imputation from Low-Pass Sequencing to Predict Merit of Beef Steers"

Along with Warren Snelling and other colleagues at the USDA MARC (Meat Animal Research Center), we recently performed a study investigating the utility of imputation from low pass sequencing data in cattle in the context of genomic prediction for beef steers. This study is now published in MDPI Genes and can be accessed at the following link [0]. In this blog post, we briefly review the motivations behind this study and outline the main results.

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