Joe is a statistical geneticist who has published scientific papers in the most selective scientific journals like Nature, Science, Nature Genetics, and PNAS. Prior to founding Gencove, he was a professor at New York Genome Center and Columbia University, and he holds a PhD in Human Genetics from the University of Chicago.
NEW
Solutions for cattle, pig, soybean, maize and rice
Whole genome information at the cost of genotyping arrays
Gencove's low-pass sequencing technology delivers cost-efficient and highly accurate variant calls across the whole genome.
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Our Technology
Gencove's cloud based imputation and analysis software transforms very low-coverage sequencing reads into over 99% accurate variant calls across the whole genome.
> 10x more data than genotyping arrays
> 99% accurate variant calls across the whole genome
> 10x reduction in cost relative to whole genome sequencing
Flexible updates and setup of new species
Or Learn more about our Full Sequencing Service
Applications
Human
Polygenic risk score calculations
Ancestry analysis
New rare variant discovery
CNV analysis
GWAS
Agrigenomics
Available solutions: cattle, pig, chicken, maize, soybean, rice
Genomic selection
Marker assisted breeding
QTL mapping
Parentage analysis
Breed/variety analysis
Companion animal and model organism
Available solutions: dog, cat, mouse, rat
Breed and strain analysis
Parentage analysis
GWAS
Use Cases
GWAS
Baker Institute - Genomic risk in celiac disease
Baker Institute is developing a genomic risk score that can help predict risk of celiac disease that is yet to manifest itself. Gencove’s low-pass sequencing will be used to establish the validity and utility of genomic risk approaches for identifying individuals at high risk.
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Biobank
University of Michigan - PSID
The Panel Study of Income Dynamics (PSID) is the world’s longest running household panel survey. Gencove’s low-pass sequencing is being used to add genomic information to the study with the aim of fully understanding the interplay of genetics and environment over the life course of the participants.
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Animal genomics
Broad Institute - Darwin’s Dogs
Darwin's Dogs is a crowd-sourced genomics project studying how the dog genome has changed through history. Using low-pass sequencing, researchers are studying how genetics shapes behaviour, and psychiatric and neurological diseases in both dogs and people.
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Conservation genomics
Stanford University - Conservation Genomics
The program is developing tools for the next generation of conservation scientists. By using low-pass genome sequencing, they are investigating the population genomics of endangered mammals like rhinos, tigers, and lions. In addition, they are sequencing sanctuary and captive animals in order to understand how the illegal wildlife trade impacts wild populations and their cosmopolitan trade routes.
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Whole genome sequencing complement
University of Utah - Gene discovery in diabetes
Researchers are applying a novel and innovative approach to accelerate gene discovery in diabetic kidney disease that integrates big data from the Utah Population Database. Deep whole-genome sequencing on select members of these pedigrees is being combined with Gencove's low-pass sequencing data on additional individuals from high-risk families.
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About Us
Gencove is a spin-out of the New York Genome Center dedicated to making genomic data more accessible and interpretable through the development of molecular and computational tools.
We are proud to be backed by a set of world-class investors like Spero Ventures, Alexandria Venture Investments, Burst Capital, Third Kind Venture Capital, Version One Ventures, Refactor Capital, SV Angel and The Syndicate Fund.
Founding Team
Joe Pickrell
CEO & Co-founder
