The adoption of high-throughput molecular breeding techniques highlights a growing need for fast, large-scale genotyping methods. When processing thousands to millions of samples per year, it is important to evaluate genotyping options for speed and efficiency.
Reducing the time to set up a new species
The Gencove low-pass sequencing and analysis platform has the speed to support genotyping needs at any scale and can be set up and ready for use in just a few weeks.
Because the Gencove platform is software-based, creating a pipeline for a new species is streamlined. First, a selection of samples that represent the diversity of the species of interest are chosen and sequenced to moderate coverage. Then, the Gencove team performs joint variant calling and haplotype phasing using a reference genome of your choice. A haplotype reference panel is then implemented to enable genotyping from future low-pass sequenced samples. The entire process only takes about a month, significantly reducing the time to implement a new genotyping pipeline compared to microarrays.