Gencove Team - Apr 22, 2024

Leading the pack: Low-pass plus capture as the next great tool for canine genomics

Dog research is at a crossroads. Like in humans, genetic tools could revolutionize veterinary care and improve the health and welfare of all dogs, but widely used genetic testing services don’t provide the information needed by researchers to achieve this vision. A collaboration between Gencove, genomic scientists, and dog breeders has developed a new solution that combines high-accuracy genetic testing with comprehensive whole genome genotyping. This dual-purpose product supports breed ancestry analysis, Mendelian disease testing, and large-scale genomics.

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Jesse Hoff, Agrigenomics Product Manager - Jan 30, 2024

A vision for the future of the cattle industry

At Gencove, we’ve long talked about Moo-res law, the trend of increasing genotype adoption in the cattle breeding world, with global genotyping in the cattle industry likely to hit 5 million samples annually by mid-decade. The successes of genomic selection are well known, led by the US dairy evaluation’s pioneering efforts over 15 years ago, with adoption following in many cattle breeding programs globally.

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Jesse Hoff, Agrigenomics Product Manager - Jul 10, 2023

Exploring the power of low-pass WGS with target capture in plant breeding

Gencove and Twist Biosciences have partnered to pressure test the utility of lp-WGS plus target capture and imputation for a major crop species, soybeans, demonstrating that lp-WGS with target capture works well in plants and covers a large panel.

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Mamad Ahangari, Data Scientist - Mar 13, 2023

Low pass sequencing plus imputation in cattle outperforms imputation from genotyping arrays

Over the past decade, the cost of genome sequencing has significantly decreased, leading to a rise in popularity of alternative sequencing methods such as low-pass whole genome sequencing instead of genotyping arrays. To meet this demand, at Gencove, we offer a cost-effective solution for generating genome-wide information by providing low-pass whole genome sequencing plus imputation as a high-throughput alternative to genotyping arrays. Our previous research has already established that low-pass whole genome sequencing outperforms traditional genotyping arrays in terms of imputation in humans (Li et al., 2021). In this blog post, we describe the results of a recent experiment where we demonstrate that imputation using low-pass whole genome sequencing is also superior to genotyping arrays in cattle.

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Maximillian Rozenblum, Applied Bioinformatics Engineer - Nov 10, 2022

New species: salmon

New pipeline available: salmon

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David Neuman, Head of Plant and Animal Genomics Sales - Aug 25, 2022

A Genotyping Platform that Changes with Your Breeding Program

Invest in a genotyping solution that changes with your breeding program. The Gencove platform ensures backward compatibility, adaptability to new markers and reference genomes, additional analyses, and continual innovation.

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David Neuman, Head of Plant and Animal Genomics Sales - Aug 23, 2022

The Importance of Speed in Plant and Animal Breeding

Improve molecular breeding efficiency with a modern genotyping approach that can be set up in a few weeks plus turns your samples around quickly!

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Jesse Hoff, Agrigenomics Product Manager - Jul 06, 2022

Get the Utility of Sequencing at the Cost of a Microarray

Gencove’s low-pass sequencing platform is at cost-per-sample price parity with many microarray assays across a wide range of species in both plants and animals. That makes Gencove the best choice for getting the utility of sequencing data at microarray prices.

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Jesse Hoff, Agrigenomics Product Manager - Jun 15, 2022

A Modern Approach to Genotyping for Plant and Animal Breeding

There’s no question that sequencing is a powerhouse of utility for genetics in breeding. However, does it meet the requirements to become a routine tool for genomic selection in breeding programs?

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Jesse Hoff, Agrigenomics Product Manager - Jun 02, 2022

The First EPD for Bovine Congestive Heart Failure from Simplot and Gencove

The Simplot and Gencove genomic EPD provides a benchmark from which bulls can be evaluated for cardiac morphology significantly reducing their calves’ morbidity and mortality and increasing their overall economic performance.

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Jesse Hoff, Agrigenomics Product Manager - Apr 28, 2022

Using a Modern Approach to Genotyping to Challenge Breed Stereotypes in Dogs

Do you rate your golden retrievers high on the scale for friendliness to strangers because they’ve been bred to demonstrate that trait or because you house an internal bias that tells you golden retrievers are friendly? These are precisely the types of questions that researchers are answering by utilizing modern, genome-wide sequencing information to better understand the association between genes and traits in dogs.

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