2. Revolutionizing Sequencing in Agriculture
We also saw major advances in the use of sequencing in agricultural genomics, particularly as sequencing becomes more cost-effective and accessible. The throughput and price-sensitivity of agricultural applications of genomics have previously meant that sequencing has not been a viable technology for widespread use, but innovation in sequencing technologies and the applications of those technologies has changed the game in 2023.
Low-pass and Ultra Low-pass Sequencing in Cattle
We shared an analysis that demonstrated that low-pass sequencing, combined with imputation, is highly effective in cattle genotyping. Even at coverage as low as 0.1x, this approach can generate comprehensive genome-wide information with sufficient accuracy for implementing genomic prediction models, marking a significant advancement in livestock genomics.
Low-pass Sequencing Plus Imputation Using Avidity Sequencing as a Cost-Effective Alternative to Traditional SBS
In a joint paper with Element Biosciences, we showcased how Avidity sequencing not only offers a cost-effective alternative to traditional sequencing but also improves data quality. This is particularly beneficial in applications like large-scale agricultural genotyping, where reducing duplication rates and costs is crucial. We also invited the Element team to join us for a webinar to explore the future possibilities of genomic applications in agriculture, you can watch it on demand here.